Detecting and targeting NTRK fusions in NSCLC: a clinical pathway tool

This tool will guide you through the best practices for detection and treatment of NTRK fusions in NSCLC. This interactive pathway provides details on the various assays that can be used to detect NTRK gene fusions, covering both the optimal approach and methods that can be used when the ideal method is not available. Our expert faculty also explain the latest advances in targeted therapies for NTRK fusion-positive NSCLC and provide their recommendations for treatment. The pathway is supplemented by summaries of recent publications to help you remain up to date with the latest clinical trial data.

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Learning objectives

After completing this activity, you will be able to: 

  • Outline biomarkers that should be tested for in patients with advanced NSCLC
  • Select appropriate strategies to identify NTRK gene fusions in NSCLC
  • Describe advances in therapies for NTRK fusion-positive tumors and evaluate the clinical data supporting their use

Activity overview

This algorithm module is available with video and text. The activity is best supported via a computer or mobile device with current versions of the following browsers: Mozilla Firefox, Google Chrome, or Safari.